专利名称：SDF-1-BASED GLYCOSAMINOGLYCAN
ANTAGONISTS AND METHODS OF USING
SAME
发明人：KUNGL, ANDREAS,WERNER, ISA,SLINGSBY, JASON,ALI, SIMI,KIRBY, JOHN, A.
申请号：EP2008008960
申请日：20081023
公开号：WO2009053064A8
公开日：
20090716
sidselrasmussen
专利内容由知识产权出版社提供
摘要：The present invention relates to novel mutants of human stromal cell-derived factor-1 which exhibit increased glycosaminoglycan (GAG) binding affinity and inhibited or down-regulated GPCR activity compared to wild type SDF-1, methods for producing these mutants and to their use for preparing medicaments for the treatment of cancer.
申请人：PROTAFFIN BIOTECHNOLOGIE AG,KUNGL, ANDREAS,WERNER, ISA,SLINGSBY, JASON,ALI, SIMI,KIRBY, JOHN, A.
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