中国最大的黑帮•1164•临床军医杂志2019年11月第47卷第11期Clin J Med Offic,Vol.47,No.11,Nov,2019
快女段林希韩天宇'，梁娜-张昊「，纪振钢'，刘宝军J周大鹏「
北部战区总医院1.骨科;2.干部病房一科;3.医务部，辽宁沈阳110016
［摘要］目的探讨生物流体止血膜在股骨粗隆间骨折手术中的应用效果。方法选取自2018年2月至2019年2月北部战区总医院收治的60例股骨粗隆间骨折患者为研究对象。采用随机数字表法将患者分为观察组与常规组，每组各30例。观察组术中髓腔及切口内给予生物流体止血膜100ml，常规组术中髓腔及切口内给予生理盐水100ml。比较两组患者术后 24h切口引流量、血红蛋白下降值，术前与术后3.5d的白细胞介素-6(IL-6)及C反应蛋白(CRP)水平。结果观察组术后24h切口引流量、血红蛋白下降值均低于常规组，差异有统计学意义(P<0.05)；观察组术后3.5d的IL4及CRP表达水平均低于常规组，差异有统计学意义(P<0.05)。结论股骨粗隆间骨折手术给予生物流体止血膜止血效果良好，能有效降低机体炎症反应。
［关键词］生物流体止血膜；内固定术；炎症因子；止血
中图分类号：R687.3|doi：10.16680/j.1671-3826.2019.11.021文章编号：1671-3826(2019)11-1164-03
周冬雨和曾志伟到底怎么回事Effect of biological fluid hemostatic membrane in the operation of intertrochanteric fracture of femur
HAN Tian-yu,LIANG Na,ZHANG Hao,JI Zhen-gang,LIU Bao-jun,ZHOU Da-peng(Department of Orthopedics,General Hospital of Northern Theater Command,Shenyang110016,China)
Abstract:Objective To investigate the effect of biological fluid hemostatic membrane in the operation of intertrochanteric fracture of femur.Methods A retrospective study was performed on60cases of patients with intertrochanteric fracture who were admitted from February2018to February2019.Patients were divided into the observation group and the conventional group,with30cases in each group.In the observation group,100ml biological fluid hemostatic membrane was given in the intramedullary cavity and incision,while in the conventional group,100ml normal saline was given in the intramedullary cavity and incision.Patients in the two groups were compared with the volume of drainage through the incision24hours after surgery,the reduction of hemoglobin,and the levels of inter-leukin-6(IL-6)and C-reactive protein(CRP)before surgery and3and5days after surgery.Results The flow of drainage through the incision and the reduction of hemoglobin in the observation group24hours after the operation were lower than those in the conventional group,with statistically significant differences(P<0.05).The expression levels of IL-6and CRP in the observation group were lower than those in the conventional group3and5days after the operation(P<0.05).Conclusion Intertrochanteric fracture of femur is treated with biological fluid hemo
static membrane,which has a good hemostatic effect and can effectively reduce the body's inflammatory response.
Key words:Biological fluid hemostatic membrane；Internal fixation；Inflammatory factors；Hemostasis
梦见把头发剪了近年来.随着社会老龄化的加重，股骨粗隆间骨折的发病率呈逐年上升趋势，老年人股骨粗隆间骨折已经成为骨科医师所面临的最主要的公共健康问题之一。微创技术与理念的发展，使得股骨粗隆间骨折行闭合复位股骨近端防旋髓内钉(proxi-mal femoral nail antirotation,PFNA)内固定成为的主要手术方式。但围术期仍然面临着失血、炎症
基金项目：国家科技重大专项子课题(2016ZX09J16103)；辽宁省自然科学基金(201602770)
第一作者：韩天宇(1977-)，男，吉林人，副主任医师，硕士沉珂照片
吉赛尔-邦臣通信作者：梁娜，E-mail:fmmuhty@sina；
周大鹏,E-mail：me3210@163 反应引发各种并发症等问题⑴。在手术技术、内固定材料及手术工具不断完善的同时，到一种迅速、有效且安全可靠的术中止血方法十分重要⑵。本研究旨在探讨生物流体止血膜在股骨粗隆间骨折手术中的应用效果。现报道如下。
1资料与方法
1.1一般资料选取自2018年2月至2019年2月北部战区总医院骨科收治的60例股骨粗隆间骨折患者为研究对象。纳入标准：年龄>65岁，符合股骨粗隆间骨折术的手术指征；未使用影响血小板、凝血功能的药物，无血液系统疾病史。采
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